20806216Chemistry for Biotechnology
Course Information
Description
This course includes topics in organic chemistry and intermolecular interactions, kinetics, chemical equilibrium including acid/base and buffer equilibrium, oxidation-reduction reactions, and thermodynamics, with an emphasis on how these topics apply to biotechnology laboratory applications. Relation of topics to laboratory experiments are emphasized. This course is not acceptable as a replacement for College Chemistry 2 (20-806-212).
Total Credits
3
Course Competencies
  1. Determine intermolecular forces present between two species and rank their relative strengths.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  2. Discuss impact of hydrogen bonding in biological systems
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  3. Discuss how intermolecular forces influence state of matter, solubility
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  4. Discuss how changes in pH affect solubility of an organic molecule
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  5. Investigate influence of pH/intermolecular forces on electrophoretic mobility of a charged species
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  6. Use collision theory to explain how reactions rates depend upon concentration, physical state and temperature.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  7. Distinguish differences between graphical representations of reactions of different kinetic orders.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  8. Determine reaction order and rate law based upon experimental concentration change, and vice-versa.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  9. Define and explain reaction rate, rate constant, reaction order, catalysts, activation energy, half-life, rate-determining step
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  10. Explain the general mechanism of enzymes in catalyzing biological reactions
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  11. Demonstrate quantitatively how the Michaelis-Menten equation relates to the determination of maximum reaction rates in enzyme kinetics
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  12. Distinguish between reaction rate and extent of reaction
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  13. Define reversible reactions, chemical equilibrium and equilibrium constants
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  14. Write an expression for the equilibrium constant for a given reversible reaction
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  15. Calculate the equilibrium constant and concentrations based upon experimental data.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  16. Calculate reaction quotient and compare to the equilibrium constant to determine extent of reaction.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  17. Use Le Chatelier's Principle to predict how changes in concentration, temperature, pressure and addition of catalyst affect shifts in equilibrium
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  18. Explore relationship between pH, concentration, equilibrium constants and limits to solubility of a biological solute.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  19. Define Arrhenius and Bronsted-Lowry acids and bases, conjugate acids and bases, salts, amphiprotic, polyprotic, oxyacids, acid and base dissociation constants
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  20. Predict the products of acid/base reactions
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  21. Predict relative strength of acids and bases based upon acid and base dissociation constants.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  22. Calculate Ka, Kb from experimental data
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  23. Calculate pH of a solution from concentration and Ka or Kb
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  24. Predict qualitativelyhow metal ions may influence acidity/basicity of a solution
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  25. Explain the difference between concentration and strength of acid or base solutions.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  26. Describe qualitatively how pH meters and acid/base indicators work.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  27. Explain the relationship between pH, pOH, hydrogen and hydroxide ion concentrations, and Kw.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  28. Explain the function and mechanism of buffer systems.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  29. Use Henderson-Hasselbach equation to determine pH of a buffer solution of given concentration.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  30. Use Henderson-Hasselbach equation to calculation the relative concentrations required to make a buffer solution of specified pH.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  31. Explain acid/base titration
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  32. Perform strong acid/strong base and weak acid/strong base titrations in lab
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  33. Explain how acid/base indicators work
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  34. Identify common buffers used in biotechnology
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  35. Explain transfer of energy in chemical reactions and distinguish between endothermic and exothermic reactions.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  36. Explain internal energy, potential energy, kinetic energy, work, heat transfer, enthalpy
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  37. Explain spontaneous and non-spontaneous reactions
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  38. Distinguish between spontaneity and reaction rate.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  39. Distinguish between spontaneous and exothermic
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  40. Explain entropy and Gibb's free energy
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  41. Predict whether a reaction results in a significant increase/decrease or little change in entropy
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  42. Calculate changes in enthalpy, entropy and Gibb's free energy for a given reaction at standard state.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  43. Predict if a chemical reaction will be spontaneousD. Distinguish between spontaneity and reaction rate.E. Distinguish between spontaneous and exothermicF. Explain entropy and Gibb's free energyF. Predict whether a reaction results in a significant increase/decrease or little change in entropyG. Calculate changes in enthalpy, entropy and Gibb's free energy for a given reaction at standard state.H. Predict if a chemical reaction will be spontaneous
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  44. Identify which species are reduced/oxidized in a redox reaction
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  45. Balance a redox reaction
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  46. Identify the parts of an electolytic cell and explain what happens at the anode and cathode.
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

  47. Predict the direction of movement of charged species in an electrolytic cell
    Assessment Strategies
    with a minimum score of 70% on written exams, quizzes, lab experiments and projects
    without referring to text and/or other reference material
    with relevant tables and/or charts as provided when necessary

This Outline is under development.